The effect of light sensitivity “sun-downing” on Alzheimer disease

The relationship between Alzheimer's disease and biological clock disruption has implications for AD treatment and symptom management. Light therapy could potentially change sleep patterns and daily rhythm disturbances in Alzheimer's patients, which can pose challenges for caregivers. Since poor sleep quality in adulthood is linked to the risk of Alzheimer's, understanding how Alzheimer's affects the biological clock could aid in its prevention. Alzheimer's patients may experience circadian disruptions due to changes in light sensitivity. Alzheimer's is a common form of dementia that entails memory loss, restlessness, and impaired judgment, particularly in the evening. The research utilized a mouse model of Alzheimer's exposed to "jet lag," wherein Alzheimer's mice demonstrated quicker adaptation due to heightened light sensitivity.